A single protein may be holding back CAR T cancer therapy

Researchers from Columbia University and University Hospital Tübingen have discovered a protein that appears to play a major role in weakening CAR T cells over time. By disabling the protein, known as NFIL3, the scientists found that these engineered immune cells remained active longer and were better able to attack…

Scientists discover gut bacteria that may help protect against autism and ADHD

Scientists have uncovered a surprising connection between a baby’s earliest biological programming, the gut microbiome, and later brain development. The findings, published in Cell Press Blue, suggest that epigenetic changes present at birth can influence how gut bacteria develop during infancy. The study also found links between specific epigenetic patterns,…

A hidden pollutant is changing how the world's forests breathe

For centuries, forests have followed a remarkably consistent rhythm. Beneath the trees, roots and microscopic organisms steadily release carbon dioxide into the atmosphere as they break down organic material and fuel plant growth. Scientists call this process soil respiration, and it represents one of the largest carbon flows on Earth.…

The secret underground system keeping the Grand Canyon alive

Every year, millions of people visiting Grand Canyon National Park stop at one of the park’s water stations. Some are standing on the rim, seeing the canyon for the first time and topping off a water bottle before continuing their trip. Others are far below, hiking through extreme heat, refilling…

This blood-feeding fly sacrifices its sight after finding a host

A strange blood-feeding fly appears to reduce its visual sensitivity after locating a host and giving up flight for good, according to new research. Known as deer keds, these biting flies are found throughout Europe, Asia, Africa, and the Americas. As adults, they use both flight and vision to search…

A stellar “Rosetta stone” reveals the source of mysterious cosmic signals

Astronomers have traced a mysterious type of repeating cosmic signal to an unusual pair of stars, providing the strongest evidence yet for the source of one of astronomy’s most puzzling phenomena. The discovery was made by an international research team led by scientists at the University of Sydney using CSIRO’s…

Your brain starts making social decisions before you do

Why do we decide to approach other people? According to new research from the Hebrew University of Jerusalem, the answer may begin unfolding in the brain several seconds before any movement takes place. The study found that social behavior is preceded by a distinctive pattern of activity that spreads across…

One fat helped pancreatic cancer grow while another cut disease in half

For years, the common assumption has been simple: eating less fat may help lower cancer risk. New research suggests the picture is much more complicated. Scientists report that when it comes to pancreatic cancer, the specific type of fat in the diet may be more important than the total amount…

New hydrogen breakthrough turns waste heat into clean fuel

Researchers at the University of Birmingham have developed a new low-temperature approach to hydrogen production that could make the clean fuel cheaper and more practical to generate. The technique could be used both in large centralized facilities and in smaller local systems that take advantage of waste heat from major…

New light-powered chip could accelerate AI and quantum computing

Scientists at Monash University have created a tiny new circuit that can generate, direct, and read information carried by light, all within a single chip. The advance marks a significant milestone for a growing area of research known as “valleytronics,” which could help drive future breakthroughs in faster computing, lower…

Your kitchen sponge is releasing microplastics every time you wash dishes

Kitchen sponges are a staple in most homes, but they may also be an overlooked source of microplastic pollution. A new study led by researchers at the University of Bonn examined how many tiny plastic particles are released from sponges during everyday dishwashing and what impact those particles have on…

This common amino acid helped mice survive deadly inflammation

A minor injury, a serious infection, or even the flu can send the body down very different paths. Some people recover quickly, while others become severely ill or die. Scientists call this path a disease trajectory, and it can be shaped by many factors, including age, sex, health history, and…

This drug delayed rheumatoid arthritis for years after treatment ended

People at high risk of developing rheumatoid arthritis (RA) may be able to postpone the disease for years with early treatment, according to new research from King’s College London. The study found that a one year course of the biologic drug abatacept significantly delayed the onset of rheumatoid arthritis, with…

Scientists discover inherited traits that break Mendel’s Laws of genetics

For more than a century, biology has been guided by the principles of inheritance first described by Gregor Mendel through his famous pea plant experiments. While those rules explain how many genetic traits are passed from parents to offspring, scientists have also known that DNA sequences are not the whole…

NASA’s X-59 is about to break the sound barrier for the first time

NASA’s X-59 quiet supersonic research aircraft is approaching one of the most important stages of its development. The experimental X-plane is set to begin a new series of test flights that will include its first trip beyond the speed of sound, along with several other key objectives for the mission.…

Hubble captures M88 on a perilous journey that could change it forever

A striking new image from the NASA/ESA Hubble Space Telescope highlights Messier 88 (M88), a spiral galaxy embarking on a journey that will unfold over hundreds of millions of years. Also known as NGC 4501, M88 lies about 63 million light-years from Earth in the constellation Coma Berenices (Berenice’s Hair).…

NASA’s Roman telescope could reveal 100,000 hidden worlds

NASA’s Nancy Grace Roman Space Telescope is expected to dramatically expand the search for planets beyond our solar system, known as exoplanets. Scientists estimate the mission could uncover about 100,000 previously unknown worlds, a remarkable increase compared to the nearly 6,300 exoplanets discovered so far through NASA missions and other…

The forgotten organ that could predict how long you live

Researchers at Mass General Brigham have uncovered evidence that the thymus, a small immune system organ long thought to lose its importance after childhood, may play a major role in adult health. Two new studies found that adults with healthier thymuses were more likely to live longer and less likely…

Why Sweden’s wolverine conservation success story is unraveling

A conservation approach once praised as a global model for helping people and predators coexist may be losing ground because of a lack of long-term government support, according to new research. In 2015, Sweden drew international attention when researchers reported that its Conservation Performance Payment (CPP) program, the oldest initiative…

This strange crystal acts like metal and glass at the same time

Creating nearly invisible wearable technologies such as smart contact lenses and ultrathin augmented reality (AR) glasses will require a radical redesign of conventional optical components. Instead of relying on bulky lenses and hardware, researchers are exploring materials that can manipulate light at the atomic scale. A team from XPANCEO, working…

Scientists found the hidden switch fueling alzheimer’s brain inflammation

The brain has its own built in immune defenses that help detect threats and protect nerve cells. But growing evidence suggests that in Alzheimer’s disease, these immune cells become stuck in a state of chronic activation. Instead of helping, they trigger ongoing inflammation that can damage the connections between brain…

Why cancer spreads more in middle age than in old age

Cancer becomes more common with age and is often harder to treat in older adults. Yet most cancer studies in mice do not reflect that reality. Fewer than 10% of mouse experiments use aged animals, with researchers typically relying on mice that roughly correspond to humans in their early 20s.…

Chimpanzees and bonobos have human-like friend circles, study finds

Humans often organize their relationships into layers, spending the most time with a small group of close friends and family while maintaining weaker connections with a larger number of acquaintances. A new international study suggests that this pattern is not unique to people. Researchers from Utrecht University and Universidad Carlos…

New solar desalination breakthrough makes fresh water without toxic brine

According to the United Nations, 2.2 billion people still do not have access to safely managed drinking water. To help meet growing demand, many regions, from California to parts of the Middle East, rely on desalination plants that convert seawater into fresh water. Traditional desalination methods such as reverse osmosis…

A quantum metasurface breakthrough could finally close the terahertz gap

Detecting light and radiation is essential across the electromagnetic spectrum, but some regions remain especially challenging. One of those is the terahertz (THz) range, which sits between microwaves and infrared light. Existing detectors for these frequencies are often slow, lack sensitivity, or depend on large, costly equipment that frequently requires…

The ocean's health may depend on a tiny microbe inside fish

Scientists have uncovered evidence that tiny microbes living inside fish may be helping drive important processes that affect the world’s oceans. The research, led by former University of Miami graduate student Anthony Bonacolta, suggests that gut bacteria and marine fish work together to produce calcium carbonate, a mineral that plays…

The secret to pigeons’ incredible navigation was hiding in their liver

How pigeons can travel hundreds of miles and still find their way home has puzzled scientists for decades. New research suggests the answer may lie in an unexpected place: the liver. According to a study published in Science, pigeons may use specialized immune cells in their livers to detect Earth’s…

Intermittent fasting triggers surprising changes in the brain

More than one billion people worldwide now live with obesity, a condition that raises the risk of cardiovascular disease, diabetes, and several types of cancer. Yet losing weight and keeping it off can be extremely difficult. The body does not simply respond to fewer calories in a straightforward way. Signals…

Omega-3 fish oil shows promise against type 2 diabetes

Fish oil may have a surprising role in the fight against insulin resistance, especially in a form of type 2 diabetes that is often overlooked. A Brazilian study published in Nutrients found that omega-3 fatty acids from fish oil reduced glucose intolerance and weakened insulin resistance in rats that were…

New 3D silicon chip breakthrough could extend Moore’s Law for years

For decades, the computing industry has followed a simple formula: make transistors smaller and pack more of them onto a chip. That strategy fueled the extraordinary rise in computing power predicted by Moore’s law. But as components approach atomic scales, engineers are increasingly running into the physical limits of silicon…