Scientists just found a tiny molecule that could change how we lose weight

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent condition is also linked to other metabolic disorders, including type 2 diabetes, cardiovascular diseases, chronic kidney disease, and cancers. Current treatment options include lifestyle interventions, bariatric surgery, and GLP-1…

Stunning “wonder reptile” discovery rewrites the origins of feathers

Body coverings such as hair and feathers have played a central role in evolution. They enabled warm-bloodedness by insulating the body, and were used for courtship, display, deterrence of enemies and, in the case of feathers, flight. Their structure is characterised by longer and more complex skin outgrowths that differ…

Scientists just measured how fast glaciers carve the Earth

Glaciers carved the deep valleys of Banff, eroded Ontario to deposit the fertile soils of the Prairies and continue to change the Earth’s surface. But how fast do glaciers sculpt the landscape? Published on August 7 in Nature Geoscience, University of Victoria (UVic) geographer Sophie Norris and her international team provide…

332 colossal canyons just revealed beneath Antarctica’s ice

Submarine canyons are among the most spectacular and fascinating geological formations to be found on our ocean floors, but at an international level scientists have yet to uncover many of their secrets, especially of those located in remote regions of the Earth like the North and South Poles. Now, an…

Scientists uncover hidden brain shortcut to weight loss without the nausea

Weight loss and diabetes drugs on the market often do not achieve long-term weight loss for patients. GLP-1 drugs target brain neurons that control appetite but frequently cause side effects. Nausea and vomiting force 70% of patients to stop treatment within a year. Syracuse University chemistry professor Robert Doyle is…

The nuclear clock that could finally unmask dark matter

For nearly a century, scientists around the world have been searching for dark matter – an invisible substance believed to make up about 80 percent of the universe’s mass and needed to explain a variety of physical phenomena. Numerous methods have been used in attempts to detect dark matter, from…

Scientists find brain cell switch that could reverse obesity’s effects

Researchers show astrocytes can be tuned to reverse some obesity-driven brain and metabolic changes, revealing untapped therapeutic potential. Credit: Shutterstock Fatty diets and obesity affect the structure and function of astrocytes1, the star-shaped brain cells located in the striatum, a brain region involved in the perception of pleasure generated by…

Scientists crack the mystery of brain cell clumps, and make them vanish

Look inside a brain cell with Huntington’s disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up surrounding proteins key for brain health, contributing to neurological disorders. How these harmful RNA clusters form in…

The hidden ways light at night damages your brain, mood, and metabolism

In a comprehensive Genomic Press Innovators & Ideas interview published today, distinguished neuroscientist Dr. Randy J. Nelson shares insights from his pioneering research on how disrupted circadian rhythms affect brain function and overall health. The interview, published in Brain Medicine, traces Dr. Nelson’s unconventional path from farm work and autopsy…

New “evolution engine” creates super-proteins 100,000x faster

In medicine and biotechnology, the ability to evolve proteins with new or improved functions is crucial, but current methods are often slow and laborious. Now, Scripps Research scientists have developed a synthetic biology platform that accelerates evolution itself — enabling researchers to evolve proteins with useful, new properties thousands of…

Breakthrough “smart” gel restores blood flow and heals diabetic wounds in days

Chronic diabetic wounds, including diabetic foot ulcers, are a significant burden for patients, as impaired blood vessel growth hinders the healing process. A recent breakthrough offers hope by combining small extracellular vesicles (sEVs) loaded with miR-221-3p and a GelMA hydrogel to target thrombospondin-1 (TSP-1), a protein that suppresses angiogenesis. This…

What really happens to your body when you stop weight loss drugs like Ozempic

Patients prescribed drugs to help them lose weight may experience a rebound in weight gain after halting their prescription, finds a meta-analysis published in BMC Medicine. The study, which analyses data for patients receiving weight loss drugs across 11 randomised trials, suggests that while the amount of weight regain varies…

Life without sunlight? Earthquake fractures fuel deep underground microbes

Chinese researchers have recently challenged the long-held belief that “all life depends on sunlight.” In a study published in Science Advances, the researchers identified how microbes in deep subsurface areas can derive energy from chemical reactions driven by crustal faulting, offering critical insights into life deep below Earth’s surface. The research…

Nature’s anti-aging hack? Jewel wasp larvae slow their biological clock

Scientists have discovered that jewel wasps can slow down their biological rate of aging. A study of jewel wasps, known for their distinctive metallic colors, has shown that they can undergo a kind of natural ‘time-out’ as larvae before emerging into adulthood with this surprising advantage. The groundbreaking study by…

Hubble just exposed a rare and violent star collision

University of Warwick astronomers have uncovered compelling evidence that a nearby white dwarf is in fact the remnant of two stars merging — a rare stellar discovery revealed through Hubble Space Telescope ultraviolet observations of carbon in the star’s hot atmosphere. White dwarfs are the dense cores left behind when…

Baby star fires a jet, then gets blasted by the fallout

Astronomers have observed an explosion in space that is pushing back against and influencing the baby star which triggered the explosion in the first place. If explosions like this one are common around young stars, then the young stars and their planets are exposed to a harsher environment than previously…

DNA from the deep reveals a hidden ocean “superhighway”

A world-first study led by Museums Victoria Research Institute has revealed that beneath the cold, dark, pressurized world of the deep sea, marine life is far more globally connected than previously imagined. Published on July 23 in Nature, this landmark study maps the global distribution and evolutionary relationships of brittle stars…

This prehistoric predator survived global warming by eating bones

About 56 million years ago, when Earth experienced a dramatic rise in global temperatures, one meat-eating mammal responded in a surprising way: It started eating more bones. That’s the conclusion reached by a Rutgers-led team of researchers, whose recent study of fossil teeth from the extinct predator Dissacus praenuntius reveals…

Scientists found the gene that makes Aussie skinks immune to deadly snake venom

A University of Queensland-led study has found Australian skinks have evolved molecular armor to stop snake venom from shutting down their muscles. Professor Bryan Fry from UQ’s School of the Environment said revealing exactly how skinks dodge death could inform biomedical approaches to treating snakebite in people. “What we saw…

Can humans regrow eyes? These snails already do

Human eyes are complex and irreparable, yet they are structurally like those of the freshwater apple snail, which can completely regenerate its eyes. Alice Accorsi, assistant professor of molecular and cellular biology at the University of California, Davis, studies how these snails regrow their eyes — with the goal of…

Scientists create mysterious molecule that could spark life in space

Researchers have for the first time isolated a compound that could open new doors in understanding the chemistry that supports life in space. Ryan Fortenberry, an astrochemist at the University of Mississippi, Ralf Kaiser, professor of chemistry at the University of Hawaii at Mānoa, and Alexander M. Mebel, computational chemist…

NASA and Japan’s XRISM just found sulfur hiding between the stars

An international team of scientists have provided an unprecedented tally of elemental sulfur spread between the stars using data from the Japan-led XRISM (X-ray Imaging and Spectroscopy Mission) spacecraft. Astronomers used X-rays from two binary star systems to detect sulfur in the interstellar medium, the gas and dust found in…

Star survives black hole and comes back for more

Lightning might not strike twice, but black holes apparently do. An international group of researchers led by Tel Aviv University astronomers observed a flare caused when a star falls onto a black hole and is destroyed. Surprisingly, this flare occurred about two years after a nearly identical flare named AT…