Looking for an early sign of LATE

Limbic predominate age-related TDP-43 encephalopathy or LATE is a recently recognized form of dementia that affects memory, thinking and social skills. It mimics Alzheimer’s disease or AD (and sometimes co-exists with it), but LATE is a different condition, with its own risks and causes. In a new study, published December…

Medical terminology can be confusing for patients

Published in JAMA Network Open, University of Minnesota Medical School researchers found there is often a disconnect between the medical language used by doctors and patient understanding. This mismatch in clinicians’ intent to speak plainly with the reality that they continue to use confusing terminology is known as jargon oblivion.…

New support for a serotonin deficit in depression

Since the 1960s, researchers have postulated that major depression stems from disruptions in the serotonin neurotransmitter system, but the evidence for that idea, though plentiful, was indirect. In fact, a recent comprehensive analysis of existing studies concluded that there was not strong evidence to support the “serotonin hypothesis.” In its…

Whales could be a valuable carbon sink, say scientists

Nature-based solutions to fight climate change take a holistic approach that promotes biodiversity and ecosystem preservation. While many efforts have focused on planting trees or restoring wetlands, researchers publishing in Trends in Ecology and Evolution on December 15 advocate for the importance of understanding the carbon sequestration potential of the…

Harmful fungal toxins in wheat: a growing threat

Wheat — the most widely cultivated crop in the world — is under growing attack from harmful toxins. Across Europe, almost half of wheat crops are impacted by the fungal infection that gives rise to these toxins, according to a study led by fungal biologist Dr Neil Brown from the…

Astronomers find that two exoplanets may be mostly water

A team led by UdeM astronomers has found evidence that two exoplanets orbiting a red dwarf star are “water worlds,” planets where water makes up a large fraction of the volume. These worlds, located in a planetary system 218 light-years away in the constellation Lyra, are unlike any planets found…

Insights get the right fish on the right plate

To alleviate hunger and food insecurity, it’s not just the size of the fish catch — it’s about who ultimately is able to put the right fish on the table. A group led by scientists at Michigan State University (MSU) have devised a way to track and measure the true…

Affecting baseball friction with different substances

Applying either rosin powder made from pine resin or a wax-like sticky substance to a baseball significantly alters the friction between the pitcher’s fingertips and the ball surface, which can in turn influence the rate at which the ball spins. These findings, published in Communications Materials, also highlight how rosin…

New study method finds two blood pressure drugs equally effective

A large VA clinical trial found that the blood pressure drug chlorthalidone (CTD) was not superior to hydrochlorothiazide (HCTZ) for the prevention of cardiovascular disease or non-cancer death. Both drugs are in a class of medications called thiazide diuretics, commonly known as water pills. They are used to help the…

Exquisite views of distant galaxies

For decades, the Hubble Space Telescope and ground-based telescopes have provided us with spectacular images of galaxies. This all changed when the James Webb Space Telescope (JWST) launched in December 2021 and successfully completed commissioning during the first half of 2022. For astronomers, the universe, as we had seen it,…

Machine learning reveals how black holes grow

As different as they may seem, black holes and Las Vegas have one thing in common: What happens there stays there — much to the frustration of astrophysicists trying to understand how, when and why black holes form and grow. Black holes are surrounded by a mysterious, invisible layer —…

A shield for 2D materials that adds vibrations to reduce vibration problems: Ultra-thin, protective, liquid-metal-printed layer improves performance of electronics, suppressing vibrational resistance

Monash University researchers have demonstrated a new, counterintuitive way to protect atomically-thin electronics — adding vibrations, to reduce vibrations. By ‘squeezing’ a thin droplet of liquid gallium, graphene devices are painted with a protective coating of glass, gallium-oxide. This oxide is remarkably thin, less than 100 atoms, yet covers centimetre-wide…

A message that resonates

Researchers from the University of Tsukuba have shown how adding a tiny resonator structure to an ultrafast electron pulse detector reduced the intensity of terahertz radiation required to characterize the pulse duration. To study proteins — for example, when determining the mechanisms of their biological actions — researchers need to…

Drought encouraged Attila’s Huns to attack the Roman empire, tree rings suggest

Hunnic peoples migrated westward across Eurasia, switched between farming and herding, and became violent raiders in response to severe drought in the Danube frontier provinces of the Roman empire, a new study argues. Hungary has just experienced its driest summer since meteorological measurements began, devastating the country’s usually productive farmland.…

Mitigating corrosion by liquid tin could lead to better cooling in fusion reactors

Researchers at Tokyo Institute of Technology and the National Institute for Fusion Science have clarified the chemical compatibility between high temperature liquid metal tin (Sn) and reduced activation ferritic martensitic, a candidate structural material for fusion reactors. This discovery has paved the way for the development of a liquid metal…

Plastic pollution kills sea urchin larvae

Sea urchin larvae raised in high levels of plastic pollution die due to developmental abnormalities, new research shows. Scientists put fertilised urchin eggs in seawater with varying levels of plastic, and compared the effects of newly made PVC pellets (called nurdles) with fragments collected on beaches. In all three concentrations…

New immune target to treat cardiovascular disease discovered: The protein, suPAR, has been found to cause atherosclerosis and kidney disease, raising potential for new treatments.

For the longest time, clinicians have treated cardiovascular disease by focusing on diabetes and blood pressure control, reducing cholesterol using medications like aspirin and statins. Despite these measures, heart disease remains the number one cause of death in the United States, with many patients having heart attacks even after their…

Cell biology: Strategy of Dis1 protein for microtubule shortening in fission yeast

Cell division, i.e., the process through which a parent cell divides into two daughter cells, is fundamental to the growth, repair, and reproduction of living organisms. During cell division, chromosomes are pulled towards opposite spindle poles through the shortening of molecular ropes known as microtubules. Microtubules, which are composed of…

Activated vitamin D3 treatment may reduce the risk of arsenic-mediated skin cancer: Calcitriol, or activated vitamin D3, may protect us from the harmful effects of arsenic in drinking water

Millions of people across the globe regularly consume arsenic-contaminated water. Exposure to arsenic has previously been associated with the development of various cancers including skin cancer. Research on the underlying molecular mechanisms regulating arsenic-mediated carcinogenesis remains sparse. Using in vitro studies, researchers from Japan demonstrate how calcitriol, or activated vitamin…

Researchers develop all-optical approach to pumping chip-based nanolasers: New technology could aid in meeting the ever-growing need to move more data faster

Researchers have developed a new all-optical method for driving multiple highly dense nanolaser arrays. The approach could enable chip-based optical communication links that process and move data faster than today’s electronic-based devices. “The development of optical interconnects equipped with high-density nanolasers would improve information processing in the data centers that…