Understanding and treating pain in children

Go ahead. Try asking a crying child or baby what’s wrong, and you most likely will come away as baffled as you were at first wail. This becomes a particular problem in hospitals where assessing pediatric pain and treating it correctly can be critical. The fact is pain can be…

Tiny sea creatures reveal the ancient origins of neurons

A study in the journal Cell sheds new light on the evolution of neurons, focusing on the placozoans, a millimetre-sized marine animal. Researchers at the Centre for Genomic Regulation in Barcelona find evidence that specialized secretory cells found in these unique and ancient creatures may have given rise to neurons…

Women given new insight into blood clot risk

New research from Queen Mary University of London, published in iScience, shows an increased risk of blood clots in women who have any combination of a particular gene mutation, oestrogen use, or common medical conditions — specifically: obesity, high blood pressure, high cholesterol, and kidney disease. Women with the Factor…

RNA for the first time recovered from an extinct species

A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note…

Predictive model could improve hydrogen station availability

Consumer confidence in driving hydrogen-fueled vehicles could be improved by having station operators adopt a predictive model that helps them anticipate maintenance needs, according to researchers at the U.S. Department of Energy’s National Renewable Energy Laboratory (NREL) and Colorado State University (CSU). Stations shutting down for unscheduled maintenance reduces hydrogen…

Live updates: Russia’s war in Ukraine

Ukraine filed lawsuits against Poland, Hungary, and Slovakia over a ban on imports of its agricultural products, Economy Minister Yuliia Svyrydenko said in a statement Monday.  “It is crucially important for us to prove that individual member states cannot ban imports of Ukrainian goods. That is why we are filing…

Canopy gaps help eastern hemlock outlast invasive insect

A new study finds that creating physical gaps in the forest canopy give eastern hemlocks more access to resources and help those trees withstand infestation by an invasive insect. The approach adds another tool to the toolkit that foresters can use to protect these trees. Eastern hemlocks are an ecologically…

Almonds as part of a healthy weight loss diet

When it comes to weight loss, nuts can get a bad rap — while they’re high in protein, they’re also high in fats, and this often deters those looking to shed a few kilos. But new research from the University of South Australia shows that you can eat almonds and…

Adaptive, efficient multi-arm phase 2 clinical trial for glioblastoma

An innovative phase 2 clinical trial led by Dana-Farber Cancer Institute in collaboration with 10 major brain tumor centers around the country and designed to find new potential treatments for glioblastoma has reported initial results in the Journal of Clinical Oncology. While none of the three therapeutics tested so far…

The missing link to make easy protein sequencing possible?

There has been a real race among scientists to create a technology that enables easy protein sequencing. Professor of Chemical Biology Giovanni Maglia of the University of Groningen has now found the missing piece in the puzzle: a way to transport a protein through a nanopore, which allows sequencing of…

Remote work can slash your carbon footprint — if done right

Remote workers can have a 54% lower carbon footprint compared with onsite workers, according to a new study by Cornell University and Microsoft, with lifestyle choices and work arrangements playing an essential role in determining the environmental benefits of remote and hybrid work. The study, published in the Proceedings of…

A suit of armor for cancer-fighting cells

In recent years, cancer researchers have hailed the arrival of chimeric antigen receptor T cell (CAR T) therapy, which has delivered promising results, transforming the fight against various forms of cancer. The process involves modifying patients’ T-cells to target cancer cells, resulting in remarkable success rates for previously intractable forms…

Possible new treatment for triple-negative breast cancer

Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer. Schug’s paper — titled, “Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and…

New research highlights importance of equity in education

A new study looks at the impact of learning environments on the academic success of racialized students. Compared to their peers, these students feel they have less control in their academic environment, less confidence and self-efficacy in their academic abilities, and weaker connections to other students and professors. The University…

The pace of climate-driven extinction is accelerating

Climate change is causing extinctions at an increasing rate, a new study by the University of Arizona researchers shows. They surveyed populations of the Yarrow’s spiny lizard in 18 mountain ranges in southeastern Arizona and analyzed the rate of climate-related extinction over time. “The magnitude of extinction we found over…

Markers can predict how children will tolerate sweetened medicine

Although there are some cultural exceptions to the rule, medicines for children are often given in liquid form that is sweetened to make it taste good. But not every child experiences the same medicine in the same way. A multidisciplinary research group specializing in pediatrics, genetics, and psychophysics, co-led by…

Buried ancient Roman glass formed substance with modern applications

Some 2,000 years ago in ancient Rome, glass vessels carrying wine or water, or perhaps an exotic perfumes, tumble from a table in a marketplace, and shatter to pieces on the street. As centuries passed, the fragments were covered by layers of dust and soil and exposed to a continuous…

Individual neurons mix multiple RNA edits of key synapse protein, fly study finds

Neurons are talkers. They each communicate with fellow neurons, muscles or other cells by releasing neurotransmitter chemicals at “synapse” junctions, ultimately producing functions ranging from emotions to motions. But even neurons of the exact same type can vary in their conversational style. A new study in Cell Reports by neurobiologists…

Scientists call for a tree planting drive to help tackle heatwaves

Adding more natural areas across our towns and cities could cool them by up to 6°C during heatwaves, according to new research from the University of Surrey’s Global Centre for Clean Air Research (GCARE). After a year of monitoring temperatures in four distinct areas of Guildford, England, researchers found that…

Telecare cuts costs, boosts quality of life for dementia patients

A UCSF telecare program that improves outcomes for patients with dementia and lightens the load for unpaid caregivers also has the surprising bonus of cutting Medicare costs, according to UC San Francisco research. In the study, publishing in JAMA Internal Medicine on Sept. 18, 2023, researchers, led by UCSF, compared…

Tracking down the formation of cardenolides in plants

Scientists at the Max Planck Institute for Chemical Ecology in Jena are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a study published in the journal Nature Plants, they present two enzymes from the CYP87A family as key enzymes that catalyze…