Mature ‘lab grown’ neurons hold promise for neurodegenerative disease: Researchers advanced the age of human neurons beyond what was previously possible

Northwestern University-led researchers have created the first highly mature neurons from human induced pluripotent stem cells (iPSCs), a feat that opens new opportunities for medical research and potential transplantation therapies for neurodegenerative diseases and traumatic injuries. Although previous researchers have differentiated stem cells to become neurons, those neurons were functionally…

Artificial nerve cells — almost like biological: Ion-tunable antiambipolarity in mixed ion-electron conducting polymers enables biorealistic organic electrochemical neurons

Researchers at Linköping University (LiU), Sweden, have created an artificial organic neuron that closely mimics the characteristics of biological nerve cells. This artificial neuron can stimulate natural nerves, making it a promising technology for various medical treatments in the future. Work to develop increasingly functional artificial nerve cells continues at…

Scientists develop novel mRNA delivery method using extracellular vesicles: Technique used to initiate collagen replacement in photoaged skin suggests potential for other mRNA and gene therapies

A team of researchers led by The University of Texas MD Anderson Cancer Center has developed a novel delivery system for messenger RNA (mRNA) using extracellular vesicles (EVs). The new technique has the potential to overcome many of the delivery hurdles faced by other promising mRNA therapies. In the study,…

Martian meteorite contains large diversity of organic compounds: Tissint, which crash landed in Morocco more than 11 years ago, is one of only five Martian meteorites that have been observed as they fell to Earth

The Martian meteorite Tissint contains a huge diversity of organic compounds, found an international team of researchers led by Technical University of Munich and Helmholtz Munich’s Philippe Schmitt-Kopplin and including Carnegie’s Andrew Steele. Their work is published in Science Advances. Tissint, which crash landed in Morocco more than 11 years…

Predisposition to accidental awareness under anesthesia identified by neuroscientists: New markers in brain structures and function could help identify people who require higher than average dose of anesthetic

Brain structures which could predict an individual’s predisposition to accidental awareness under anaesthetic have been identified for the first time by neuroscientists in Trinity College Dublin. The findings, just published in the journal Human Brain Mapping, could help identify individuals who may require higher than average doses of anaesthetic. Although…

Faster knee for better walking: Scientists find knee extension velocity while seated strongly predicts walking performance in elderly patients after total knee arthroplasty

Osaka Metropolitan University scientists delved into the relationship between gait function and knee extension velocity after total knee arthroplasty and compared the effects of various factors on walking. The results reveal that knee extension velocity, measured while seated, on the operated side was the most important determinant of gait function.…

Screen-printing method can make wearable electronics less expensive

The glittering, serpentine structures that power wearable electronics can be created with the same technology used to print rock concert t-shirts, new research shows. The study, led by Washington State University researchers, demonstrates that electrodes can be made using just screen printing, creating a stretchable, durable circuit pattern that can…

Live updates: Russia’s war in Ukraine

A Ukrainian soldier in the contested eastern town of Soledar told CNN Wednesday evening that he and his comrades remained in the settlement, but the situation was “very difficult” and the next 24 hours or so would be critical. “It is tough here, but we are more alive than anyone else,” the…

Flights delayed across the US after FAA system outage

Travelers wait in the terminal after flights were delayed and canceled due to an FAA outage. (Saul Loeb/AFP/Getty Images) When air traffic control officials realized they had a computer issue late Tuesday, they came up with a plan: Reboot the system when it would least disrupt air travel Wednesday morning.  …

New study findings add to the debate over long Covid symptoms | CNN

CNN  —  The majority of long Covid symptoms resolve within the first year after infection for people with mild cases of Covid-19, according to a large study conducted in Israel. “Mild disease does not lead to serious or chronic long term morbidity in the vast majority of patients,” said study…

Computer models determine drug candidate’s ability to bind to proteins

Combing computational physics with experimental data, University of Arkansas researchers have developed computer models for determining a drug candidate’s ability to target and bind to proteins within cells. If accurate, such an estimator could computationally demonstrate binding affinity and thus prevent experimental researchers from needing to investigate millions of chemical…